Smiles: CN1CCN(CC1)C1=CC2=C(C(=C1)OCC(F)(F)F)C1=CN=C(C=C1N2C(C)C)NC1=CC=NC(=N1)C1C=NN(C=1)S(=O)(=O)C1CC1
but not but not with the wild-type HTT protein
InChi: InChI=1S/C24H17ClN2O3/c1-29-15-10-12-16(13-11-15)30-23-21(25)14-26-27(24(23)28)22-19-8-4-2-6-17(19)18-7-3-5-9-20(18)22/h2-14
CF53 (Compound 28) binds to both the BD1 and BD2 domains of BRD2
The Val-Cit will specifically be cleaved by catepsin B
N-(Boc-PEG4)-NH-PEG4-NH-Boc 17943 Smiles: CN1CCN(CC1)C1=CC2=C(C(=C1)OCC(F)(F)F)C1=CN=C(C=C1N2C(C)C)NC1=CC=NC(=N1)C1C=NN(C=1)S(=O)(=O)C1CC1N (Boc PEG4) NH PEG4 NH Boc is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2112737 17 2 Molecular Weight: 640. 80 Formula: C30H60N2O12 Chemical Name: tert butyl 1 {[(tert butoxy)carbonyl]amino} 3,6,9,12,18,21,24,27 octaoxa 15 azatriacontan 30 oate Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCNCCOCCOCCOCCOCCNC(=O)OC(C)(C)C InChiKey: AFDJSRZVXYKUQT UHFFFAOYSA N InChi: InChI=1S C30H60N2O12 c1 29(2,3)43