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InChiKey: IAJBQAYHSQIQRE-UHFFFAOYSA-N
InChi: InChI=1S/C22H21N8O8PS4
J Clin Invest
CAS Number: 69-78-3
Smiles: CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)C(F)(F)[C@@H]1O
CS-2660 (JNJ-38158471) Catalog No.:M13698-2 InChiKey: IAJBQAYHSQIQRE-UHFFFAOYSA-NCS 2660 (JNJ 38158471) is a well tolerated, orally available, highly selective VEGFR 2 inhibitor with IC50 of 40 nM. CS 2660 (JNJ 38158471) also inhibits closely related tyrosine kinases such as RET (c RET) and Kit (c Kit) with IC50 of 180 nM and 500 nMwhile it has no significant activity (>1 microM) against VEGFR 1 and VEGFR 3. Product information CAS Number: 951151 97 6 Molecular Weight: 364. 79 Formula: C15H17ClN6O3 Chemical Name: 1 [4 ({6 amino 5