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EGFR-IN-1 hydrochloride Catalog No.:M27662-C It reacts with all four

SKU: 78338745420

4.6
USD100.00 USD125.00

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Description

It reacts with all four DNA bases but with different efficiency: G >C > A >T

Formula: C13H16N2O4S

incorporates an E3 ligase ligand plus a PEG1 linker with terminal azide ready for conjugation to a target protein ligand

Smiles: CCOC1=CC(N)=C(C=C1)OC1C=CC(=CC=1)OCC1=CC(F)=CC=C1F

Formula: C32H45N9O3S

EGFR-IN-1 hydrochloride Catalog No.:M27662-C It reacts with all fourEGFR IN 1 hydrochloride is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 hydrochloride potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 hydrochloride displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 2227455 78 7 Molecular Weight: 551. 04

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