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Chemical Name: 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide
myristoylated (10 μM) blocks PKMζ-mediated AMPA receptor (AMPAR) potentiation
Bryonolic acid inhibits both clonogenicity and invasiveness in MCF-7 MB-231
CAS Number: 78587-05-0
O6-Benzylguanine (50 μg
(Rac)-BRD0705 - CAS# 1597440-03-3 Size:Contact [email protected] for quotation Chemical Name: 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide(Rac) BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3 inhibitor with an IC50 of 66 nM and a Kd of 4. 8 M. BRD0705 displays increased selectivity for GSK3 (8 fold) versus GSK3 (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML). Product information CAS Number: 1597440 03 3 Molecular Weight: 321. 42 Formula: C20H23N3O Chemical Name: 4 ethyl 7,7 dimethyl 4 phenyl