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CAS Number: 147591-46-6
Formula: C24H27ClN2O4
and modulates immune responses by suppressing MHC II on interferon gamma-stimulated
It blocks hyperpolarization-activated inward current (If) through cyclic nucleotide-gated cation (HCN) channels in sinoatrial node cells
PMID: 19696185
Cot inhibitor-1 Catalog No.:M11164-10 CAS Number: 147591-46-6Cot inhibitor 1 (compound 28) is a selective tumor progression loci 2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor 1 shows an inhibition of TNF alpha production in human whole blood with an IC50 of 5. 7 nM. Product information CAS Number: 915365 57 0 Molecular Weight: 553. 46 Formula: C27H27Cl2FN8 Chemical Name: 6 [({1 [2 (azepan 1 yl)ethyl] 1H 1,2,3 triazol 4 yl}methyl)amino] 8 chloro 4 [(3 chloro 4 fluorophenyl)amino]quinoline 3
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