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a diarylisoxazole
14-tetrahydroxy-8
exhibits oral bioavailability 43%
) effectively inhibits the FLT3 pathway and significant inhibits tumor growth
AAPK-25 enhances survival rate in the BALB/c nude mice tumor xenograft model
UT-34 Catalog No.:M25039-C a diarylisoxazoleUT 34 is a potent, selective and orally active second generation pan androgen receptor (AR) antagonist and degrader with IC50s of 211. 7 nM, 262. 4 nM and 215. 7 nM for wild type, F876L and W741L AR, respectively. UT 34 binds to ligand binding domain (LBD) and function 1 (AF 1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT 34 has anti prostate cancer efficacy. Product information CAS Number: 2168525 92 4 Molecular Weight:
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