MALT1-MI-2 (MI-2) - MALT1 inhibitor. CAS# 1047953-91-2 429 1338259-05-4

1338259-05-4

Atglistatin hydrochloride was generated by the addition of 25% HCl

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming

Dacinostat

Chemical Name: 3

MALT1-MI-2 (MI-2) - MALT1 inhibitor. CAS# 1047953-91-2 429 1338259-05-4MALT1 MI 2 (MI 2), CAS No. 1047953 91 2, is a highly potent and selective small molecule directly binding to MALT1 and irreversibly suppressing its protease function. MI 2 concentrated within human ABC DLBCL cells and irreversibly inhibited cleavage of MALT1 substrates with EC50 < 1 M (HBL 1 ~200 nM; TMD8 ~500 nM). This was accompanied by NF B pathway suppression, c REL nuclear localization inhibition, and NF B target gene downregulation. MI 2 was