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Sotrastaurin inhibits both T- and B-cell activations via PKC theta and beta isozymes
Formula: C33H31Cl2N5O3
InChi: InChI=1S/C21H23BrN6O5S/c22-15-3-1-2-13(6-15)10-28-5-4-18(27-28)20(30)17-9-24-12-25-21(17)26-16-7-14(19(29)8-16)11-33-34(23
InChiKey: PKCDDUHJAFVJJB-KQODVJPSSA-N
Smiles: CC(C)(C)C1=CC(CN[C@@H]2[C@H](C(C3C=CC=CC=3)C3C=CC=CC=3)N3CCC2CC3)=C(C=C1)OC
AHR antagonist 2 Catalog No.:M15610-C Sotrastaurin inhibits both T- andAHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0. 885 and 2. 03 nM for human and mouse AhR. Product information CAS Number: 2338747 54 7 Molecular Weight: 418. 37 Formula: C20H17F3N4O3 Chemical Name: N [(2S) 1 hydroxypropan 2 yl] 2 (pyridin 3 yl) 6 [4 (trifluoromethoxy)phenyl]pyrimidine 4 carboxamide Smiles:
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