Ishkanah can make your opponent lose one life for each spider you control
Each deck has its own featured, Mythic Rare card that uses specific mana colours that the decks are based around: the Green and White Byrke, Long Ear of the Law and Blue/Red Bria, Riptide Rogue cards, as shown below
When one of those abilities resolves, it will put counters only on Mutants, Ninjas, and/or Turtles that dealt combat damage to the appropriate player
Nowadays, Serra Angel doesnt make enough of an impact to be worth spending 5 mana on, especially in Commander
Best Rare: Nettlecyst Honorable Mention: Search the Premises There are countless decks that wish they could run Cranial Plating or All That Glitters as an alternative win condition, but lack the color identity to do so
Cards like Disintegrate and Anger of the Gods dont send anything to exile because the targets cant be dealt lethal damage