HDAC-IN-4 15439 [O-]C(=O)[C@H](CC1C=CC(=CC=1)OC(=O)N1CCCC1)NC(=O)[C@@H]1CCCN1S(=O)(=O)C1C=CC=CC=1

[O-]C(=O)[C@H](CC1C=CC(=CC=1)OC(=O)N1CCCC1)NC(=O)[C@@H]1CCCN1S(=O)(=O)C1C=CC=CC=1

CAS Number: 1320288-19-4

produces a protein that is misfolded and does not reach the cell membrane

1-diyl)bis((carboxymethyl)azanediyl))diacetate

2007 Aug 18

HDAC-IN-4 15439 [O-]C(=O)[C@H](CC1C=CC(=CC=1)OC(=O)N1CCCC1)NC(=O)[C@@H]1CCCN1S(=O)(=O)C1C=CC=CC=1HDAC IN 4 is a selective HDAC6 and HDAC10 inhibitor with pIC50s of 7. 2 and 6. 8 in BRET assay, respectively. Antitumoral activity. Product information CAS Number: 1252003 13 6 Molecular Weight: 335. 40 Formula: C20H21N3O2 Chemical Name: N hydroxy 4 ({2 methyl 1H, 2H, 3H, 4H, 9H pyrido[3, 4 b]indol 9 yl}methyl)benzamide Smiles: CN1CC2=C(CC1)C1=CC=CC=C1N2CC1=CC=C(C=C1)C(=O)NO InChiKey: JVELXRPQMVXDDP UHFFFAOYSA N InChi: InChI=1S C20H21N3O2 c1 22 11 10