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PF-03084014 dodrine hydrochloride InChiKey: ZUZPCOQWSYNWLU-VIFPVBQESA-N

SKU: 4645503837

4.2
USD100.00 USD143.00

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Description

InChiKey: ZUZPCOQWSYNWLU-VIFPVBQESA-N

PF-03084014 dodrine hydrochloride InChiKey: ZUZPCOQWSYNWLU-VIFPVBQESA-NPF 03084014 is a reversible and selective inhibitor of secretase with IC50 value of 6. 2 nM . The Notch signaling pathway is triggered by the interaction of Notch ligand and Notch receptor located in the membrane of the adjacent cell. Then the NICD fragment is released through the cleavage caused by secretase and subsequently regulates the transcription of the downstream genes. Since Notch signaling pathway appears to be important in the development

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