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Gefitinib-based PROTAC 3 - CAS# 2230821-27-7 size:10mg solid is a Class I HDAC

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Description

is a Class I HDAC inhibitor (IC50 values are 0

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

Gehling VS

which plays an important role in nucleotide metabolism and a variety of development processes

10 nM) reduces high-glucose (HG)-induced human renal glomerular endothelial cells (HRGECs) viability

Gefitinib-based PROTAC 3 - CAS# 2230821-27-7 size:10mg solid is a Class I HDACGefitinib based PROTAC 3, CAS No. 2230821 27 7, also known as Gefitinib based PROTAC 3 is a VHL recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11. 7 nM and 22. 3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R). Product information CAS Number: 2230821 27 7 Molecular Weight: 934. 51 Formula: C47H57ClFN7O8S Synonym: Gefitinib based PROTAC 3 NTN21277 NTN 21277 NTN 21277 Chemical Name: (2S,4R) 1 ((S) 2 (3 (2

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