AKT-IN-VIII - CAS# 612847-09-3 size:Contact [email protected] for quotation Chemical Name: N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1

Chemical Name: N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1

Vuylsteke P

3791/51519

BMH-21 (50 mg/kg

PubMed PMID: 20086151

AKT-IN-VIII - CAS# 612847-09-3 size:Contact [email protected] for quotation Chemical Name: N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1AKT IN VIII, CAS No. 612847 09 3, also known as AKTi 1 2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKI activity and aryl hydrocarbon receptor pathway. AKT IN VIII suppresses hyperthermia induced Ndrg2 phosphorylation in gastric cancer cells. AKT IN VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium