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The closest thing to what I'm looking for is Avenger of Zendikar, which basically wins you the game if your opponents don't deal with it during that turn cycle, which is probably good enough

Its secrets had always lived within one rune-carved head

I dont know that it ever exceeds Bracket 2 or so, but it has potential around that power level

For more generalized removal you have Despark, Anguished Unmaking, Mortify, and Return to Dust

(It cant be blocked except by two or more creatures.) In the darkness, Lana reached for Shays hand and squeezed it for comfort

Triple-S is definitely my number-one Constructed Simic card of all time