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Terbogrel blocks the thromboxane A2/endoperoxide receptor on washed human platelets with an IC50 of 11 ± 6 nM (n = 2) and with an IC50 of 38 ± 1 nM (n = 15) in platelet-rich plasma
InChiKey: AVXDZNOJIVOGRR-UHFFFAOYSA-N
4 μM by microscale thermophoresis (MST) measurements
55(10):1079-85
PF-05180999 is a phosphodiesterase 2A (PDE2A) inhibitor
DprE1-IN-2 Demethyl-β-amyrone Terbogrel blocks the thromboxane A2/endoperoxideDprE1 IN 2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1 IN 2 has antituberculosis effect. Product information CAS Number: 1615713 87 5 Molecular Weight: 368. 43 Formula: C19H24N6O2 Chemical Name: 1 {[6 (dimethylamino) 5 methylpyrimidin 4 yl]methyl} N (2 hydroxyethyl) 6 methyl 1H pyrrolo[3,2 b]pyridine 3 carboxamide Smiles: CN(C)C1=NC=NC(CN2C=C(C(=O)NCCO)C3=NC=C(C)C=C23)=C1C InChiKey: BLNAAWXUNQHVNT UHFFFAOYSA N InChi:
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