Vc-MMAD ibefradil 2HCl with maximal inhibition of 58%

with maximal inhibition of 58% to 75% at the dose of 30 mg/kg/day

Smiles: OC(=O)CCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChi: InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3

24 hours) blocks GTP-KRAS formation in H2122

which shows IC50 values of 15 nM and 2

Vc-MMAD ibefradil 2HCl with maximal inhibition of 58%Vc MMAD (VCMMAD) is a drug linker conjugate for antibody drug conjugation (ADC). Vc MMAD is consisted of the ADCs linker (Val Cit) and the potent tubulin inhibitor (MMAD). Product information CAS Number: 1401963 17 4 Molecular Weight: 1369. 71 Formula: C70H104N12O14S Chemical Name: {4 [(2S) 5 (carbamoylamino) 2 [(2S) 2 [6 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)hexanamido] 3 methylbutanamido]pentanamido]phenyl}methyl N [(1S) 1 {[(1S) 1 {[(3R,4S,5S) 3