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Epub 2014 Aug 13
3-diethyl-7-methyl-2
AG1749 sodium
367–371 (1985)
3R)-2-(2-chloroacetyl)-1-(4-(methoxycarbonyl)phenyl)-2
Tariquidar 60314 Epub 2014 Aug 13Tariquidar, also known as XR9576, is a P glycoprotein (P gp) inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non competitively binds to the p glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Product information CAS