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SC-26196 inhibited the desaturation of 2 microM [1-14C] 18:2n-6 by 87-95% in cultured human skin fibroblasts
thereby inhibiting tumor cell proliferation
InChi: InChI=1S/C16H17ClN2OS/c17-12-3-1-2-11-8-14(21-15(11)12)16(20)18-13-9-19-6-4-10(13)5-7-19/h1-3
UCB9608 (compound 44) is a potent
thus potentiating the antitumor efficacies of various chemotherapeutic agents
Destruxin B - CAS# 2503-26-6 nelate SC-26196 inhibited the desaturation ofDestruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl 2 Family dependent mitochondrial pathway in human nonsmall cell lung cancer cells. Destruxin B significantly activates caspase 3 and reduces tumor cell proliferation through caspase mediated apoptosis, not only in vitro but also in vivo. Product information CAS