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with an IC50 of 12 nM
Shenderovich M
InChiKey: KURQKNMKCGYWRJ-HNNXBMFYSA-N
Penttilä K
Delvaeye T
RSL-3 - CAS# 1219810-16-8 0434 with an IC50 of 12RSL 3, CAS No. 1219810 16 8, is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL 3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3 rslR cells. Product information CAS Number: 1219810 16 8 Molecular Weight: 440. 88 Formula: C23H21ClN2O5 Synonym: RSL 3 RSL 3 RSL3 Chemical Name: Methyl(1S,3R) 2 (2
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