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is a potent and soluble IRE1α inhibitor
PubMed PMID: 19926852
at doses of 3
In the CT-26 tumor model
InChi: InChI=1S/C22H20ClF3N4O3S/c1-15-8-9-27-30(15)17-4-2-16(3-5-17)21(31)28-10-12-29(13-11-28)34(32
PF-06291874 7553 is a potent and solublePF 06291874 is a highly potent, non peptide and orally active glucagon receptor antagonist. PF 06291874 is under the study for type 2 diabetes mellitus (T2DM). Product information CAS Number: 1393124 08 7 Molecular Weight: 503. 51 Formula: C26H28F3N3O4 Chemical Name: 3 ({4 [(1S) 1 {3,5 dimethyl 4 [4 (trifluoromethyl) 1H pyrazol 1 yl]phenoxy}butyl]phenyl}formamido)propanoic acid Smiles:
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