ARD-266 12896 exhibits a significant neuroprotective effect

exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury

InChi: InChI=1S/C9H4Br4O2/c10-5-3-4(1-2-6(14)15)7(11)9(13)8(5)12/h1-3H

IDH2-C100 was used at 1-5 µM in vitro and cellular assays

Smiles: CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C1=CN=CC=N1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1

Interactions of sulfaproxyline and of sulfamerazine with blood proteins]

ARD-266 12896 exhibits a significant neuroprotective effectARD 266 is a highly potent and VHL E3 ligase based androgen receptor (AR) PROTAC degrader. ARD 266 effectively induces degradation of AR protein in AR positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0. 2 1 nM. Product information Molecular Weight: 915. 51 Formula: C52H59ClN6O7 Chemical Name: (2S,4R) 4 hydroxy 1 [(2R) 3 methyl 2 (3 methyl 1,2 oxazol 5 yl)butanoyl] N [(1S) 3 oxo 1 phenyl 3 {4 [2 (4 {[(1r,3r) 3 (3 chloro 4