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JLK 6 njugates 15 hydrochloride SU1498 induces a marked increase

SKU: 94205622489

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Description

SU1498 induces a marked increase in lipids and a decrease in glycerophosphocholine

21-hexaoxo-16-propan-2-yl-1

17)15-8-7-14

InChiKey: CPMGENCTAWBLNW-UHFFFAOYSA-N

with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R

JLK 6 njugates 15 hydrochloride SU1498 induces a marked increaseJLK 6, an isocoumarin, is a selective inhibitor of secretase, with an IC50 value between 10 M 1 mM [1, 2]. The enzyme secretase catalyzes the cleavage of Amyloid precursor protein (APP) to produce Amyloid peptide (A). A is a part of the plaque present in the brain of patients with Alzheimers disease. secretase also targets other substrates like Notch. Notch is a transmembrane protein which is involved in important functions during different stages in

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