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Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1
dogs and monkeys
binding at the PIF-pocket
Formula: C6H11NO2
tumor regression
PY-60 Catalog No.:M16115-C Chelerythrine inhibits the BclXL-Bak BH3PY 60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1. 4 M. PY 60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity. Product information Molecular Weight: 313. 37 Formula: C16H15N3O2S Chemical Name: 5 phenyl N [3 (1, 3 thiazol 2 yl)propyl] 1, 2 oxazole 3 carboxamide Smiles: O=C(NCCCC1=NC=CS1)C1C=C(ON=1)C1C=CC=CC=1 InChiKey: UFASECSYKSMYET
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