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Epub 2018 Nov 13
SB-267268 (60 mg/kg
7 cells with an IC50 of 10
InChiKey: UBMTZODMRPHSBC-UHFFFAOYSA-N
22(1):151-9
Cilofexor mol hemisulfate Epub 2018 Nov 13Cilofexor (GS 9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC50 of 43 nM. Cilofexor has anti inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research. Product information CAS Number: 1418274 28 8 Molecular Weight: 586. 85 Formula: C28H22Cl3N3O5 Chemical Name: 2 [3 (2 chloro 4 {[5 cyclopropyl 3 (2,6 dichlorophenyl) 1,2
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