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shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ
100% closure was observed in the CAY-treated group at day 14
Formula: C14H14N4O2
LD50: Mice 335mg/kg (i
CAS Number: 2123480-72-6
Benazepril tert-Butyl Ester-d5 nd Z shows slightly selective over p38βProduct information CAS Number: 1356010 96 2 Molecular Weight: 485. 63 Formula: C28H36N2O5 Chemical Name: ethyl (2S) 2 {[(3S) 1 [2 (tert butoxy) 2 oxoethyl] 2 oxo 2,3,4,5 tetrahydro 1H 1 benzazepin 3 yl]amino} 4 [(2,3,4,5,6 H)phenyl]butanoate Smiles: [2H]C1C(CC[C@H](N[C@H]2CCC3=CC=CC=C3N(CC(=O)OC(C)(C)C)C2=O)C(=O)OCC)=C([2H])C([2H])=C([2H])C=1[2H] InChiKey: QNLLWVSHZXSUNF HVSPQWTBSA N InChi: InChI=1S C28H36N2O5 c1 5 34 27(33)23(17 15 20 11 7 6 8 12
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