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Tat-beclin 1 TFA 15009 85(6):1290-1302

SKU: 70563948409

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Description

85(6):1290-1302

ARRY-520 had low nanomolar antiproliferative activity in tumor cell lines and specifically inhibits KSP (kinesin-5 or Eg5)

Pipofezine dihydrochloride monohydrate

DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

PubMed PMID: 23949446

Tat-beclin 1 TFA 15009 85(6):1290-1302Tat beclin 1 TFA, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR 1 (GLIPR2). Tat beclin 1 TFA decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV 1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV). Product

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